New research indicates that people who stop using new slimming jabs like Wegovy and Mounjaro can put back on reduced body mass much more quickly than those who stop conventional lifestyle programs.
Published data in a prominent health publication points out that while obese individuals often shed substantial amounts of their total mass while using the jabs, the weight comes back at an estimated rate of 0.8 kg per month after stopping.
"Users purchasing these drugs must be aware of the danger of rapid weight regain when the therapy concludes," stated lead investigator Dr. Susan Jebb.
That rate of regain implies a return to starting mass within about a year and a half.
Analyzing Treatments
The research, which examined dozens of studies involving over 9,000 of patients, compared the outcomes of the injectable medications with other pills.
Scientists point out that people who shed pounds through dieting typically experience a less rapid weight regain—around 0.1 kg a month—after stopping.
Understanding the Quick Regain
Experts suggest the way of the injections accounts for the accelerated weight return.
The injections imitate a body's own chemical called GLP-1, which controls hunger.
"Long-term administration of the hormone levels several times higher than normal could lead to the body to produce less of its endogenous hormone, and may also diminish responsiveness to its effects," noted Dr. Adam Collins, a dietetics specialist.
"Withdrawal of this medication leads to appetite is no longer kept in check, making overeating far more likely."
A Chronic Condition?
Medical guidelines suggest the jabs for people with weight-linked medical conditions, accompanied by recommended lifestyle changes.
Many experts argue that, considering the likelihood of relapse, the treatment is often ongoing.
This view is reinforced by pharmaceutical companies, who state that the findings "highlight the chronic nature of obesity," akin to managing diseases like high blood pressure.
Patient Experiences
People who have discontinued the medication explain a intense return of cravings.
"It was like something activating and you're instantly starving," said a patient.
This challenge is compounded if individuals have not adopted sustainable lifestyle or habit modifications during treatment.
Significant Use
Figures suggest that millions of adults in the UK have used these injections in the past year, with demand being substantial.
- Use is more common among women than men.
- The 40s and 50s age group shows the highest usage rates.
- A large proportion obtain the medications through private prescriptions rather than public health services.
Ultimately, clinicians caution that while GLP-1 drugs are powerful tools for shedding pounds, they are not a standalone fix and long-term success hinges on ongoing lifestyle management.
